Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXM1 | Q08050 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | FABP1 | P07148 | 1/20 | 0.48 |
| ▸ | FABP6 | P51161 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.47 |
| ▸ | ITGAV | P06756 | 5/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.47 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29985926 | 0.86 | SMN1; SMN2 (0.54) | FOXM1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29045774 | 0.86 | SMN1; SMN2 (0.54) | FOXM1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29986882 | 0.82 | FOXM1 (0.61) | FOXM1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29986797 | 0.82 | F2 (0.70) | FOXM1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6852321 | 0.80 | LMNA (0.64) | FOXM1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29045836 | 0.79 | FOXM1 (0.52) | FOXM1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29045841 | 0.77 | FOXM1 (0.63) | FOXM1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29045793 | 0.76 | APP (0.60) | FOXM1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29045855 | 0.76 | FOXM1 (0.55) | FOXM1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29045806 | 0.75 | FOXM1 (0.54) | FOXM1NPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304502-B | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-10-18 | — | — | CN | disclosed |
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |