Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375432 | 1.00 | TRPV1 (0.54) | TRPV1KMT2AMEN1TDP1KCNMA1 | |
| SCHEMBL22204030 | 0.84 | TRPV1 (0.51) | TRPV1KMT2AMEN1TDP1KCNMA1 | |
| SCHEMBL299472 | 0.83 | LMNA (0.47) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL13067842 | 0.81 | KDM4E (0.46) | TRPV1KMT2AMEN1KCNMA1SMN1; SMN2 | |
| SCHEMBL13835625 | 0.81 | P2RX1 (0.45) | KMT2AMEN1TDP1KCNMA1MAPT | |
| SCHEMBL27785087 | 0.79 | MEN1 (0.50) | TRPV1KMT2AMEN1TDP1SMN1; SMN2 | |
| SCHEMBL6742896 | 0.79 | SORT1 (0.35) | TRPV1KDM4ERORC | |
| SCHEMBL1766630 | 0.78 | TRPV1 (0.45) | TRPV1KMT2AMEN1TDP1KCNMA1 | |
| SCHEMBL22204018 | 0.78 | TRPV1 (0.50) | TRPV1KMT2AMEN1KCNMA1SMN1; SMN2 | |
| SCHEMBL29409940 | 0.78 | MEN1 (0.49) | TRPV1KMT2AMEN1TDP1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427427-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |