Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 13/20 | 0.51 |
| ▸ | RBBP4 | Q09028 | 13/20 | 0.51 |
| ▸ | SUZ12 | Q15022 | 13/20 | 0.51 |
| ▸ | EZH2 | Q15910 | 13/20 | 0.51 |
| ▸ | AEBP2 | Q6ZN18 | 13/20 | 0.51 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113133 | 0.91 | EED (0.49) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21157348 | 0.85 | EED (0.65) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL28958911 | 0.84 | EED (0.54) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21240625 | 0.84 | EED (0.57) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL29986331 | 0.83 | TBK1 (0.40) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113362 | 0.83 | TBK1 (0.42) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964730 | 0.83 | EED (0.53) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113182 | 0.82 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113310 | 0.81 | EED (0.68) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113258 | 0.79 | EED (0.56) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790160-B | Pyrido five-membered aromatic ring compound, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2022-11-15 | — | — | CN | disclosed |