Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 3/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 3/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113386 | 0.90 | TBK1 (0.41) | TBK1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL29985806 | 0.83 | EED (0.51) | TBK1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL21113387 | 0.81 | TBK1 (0.38) | TBK1RETSMN1; SMN2POLBMEN1 | |
| SCHEMBL21157289 | 0.78 | EZH2 (0.44) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113133 | 0.77 | EED (0.49) | TBK1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL21113406 | 0.76 | GPR119 (0.41) | TBK1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL21113055 | 0.74 | EED (0.36) | TBK1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL21113397 | 0.74 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113181 | 0.71 | LMNA (0.36) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113156 | 0.71 | GPR119 (0.42) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790160-B | Pyrido five-membered aromatic ring compound, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2022-11-15 | — | — | CN | disclosed |