Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29985588 | 0.98 | KDM4E (0.67) | KDM4EALDH1A1JAK2LMNAGAA | |
| SCHEMBL29045792 | 0.86 | KDM4E (0.63) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29045812 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12204779 | 0.76 | ALDH1A1 (0.61) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL12204698 | 0.76 | ALDH1A1 (0.65) | KDM4EALDH1A1DRD2DRD4HTR1A | |
| SCHEMBL2352175 | 0.76 | KDM4E (0.69) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL22627319 | 0.75 | GAA (0.53) | KDM4EALDH1A1JAK2LMNAGAA | |
| SCHEMBL2474305 | 0.74 | ALDH1A1 (0.88) | KDM4EALDH1A1LMNAGAAHTR1A | |
| SCHEMBL2469303 | 0.74 | ALDH1A1 (0.63) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL3861777 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1LMNAMAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304502-B | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-10-18 | — | — | CN | disclosed |
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |