Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.46 |
| ▸ | THRA | P10827 | 5/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 8/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651241 | 0.79 | THRB (0.51) | THRBTHRA | |
| SCHEMBL28924887 | 0.77 | THRB (0.62) | THRBTHRACDK2 | |
| SCHEMBL28651437 | 0.77 | THRB (0.51) | THRBTHRA | |
| SCHEMBL29417471 | 0.76 | THRB (0.52) | THRBTHRA | |
| SCHEMBL28651291 | 0.75 | THRB (0.52) | THRBTHRA | |
| SCHEMBL22632821 | 0.75 | THRB (0.52) | THRBTHRA | |
| SCHEMBL21940317 | 0.73 | THRA (0.48) | THRBTHRAPARP1 | |
| SCHEMBL28442792 | 0.73 | THRB (0.56) | THRBTHRA | |
| SCHEMBL28641722 | 0.71 | THRB (0.45) | THRBTHRA | |
| SCHEMBL28646663 | 0.70 | THRB (0.45) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278013-B | 2, 6-disubstituted 1,2, 4-triazine-3, 5-diketone compound and preparation method and application thereof | 昆药集团股份有限公司 | 2022-09-23 | — | — | CN | disclosed |