Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639975 | 0.83 | GPR119 (0.52) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL10052777 | 0.79 | CHRM2 (0.49) | CHRM2CHRM1CHRM3GPR119PREP | |
| SCHEMBL720548 | 0.79 | CHRM2 (0.49) | CHRM2CHRM1CHRM3GPR119PREP | |
| SCHEMBL720547 | 0.79 | CHRM2 (0.49) | CHRM2CHRM1CHRM3GPR119PREP | |
| SCHEMBL29986931 | 0.77 | ALDH1A1 (0.38) | GPR119HSD11B1NPC1ALDH1A1MAPT | |
| SCHEMBL1029892 | 0.76 | CHRM2 (0.48) | CHRM2CHRM1CHRM3GPR119KCNK3 | |
| SCHEMBL1029854 | 0.76 | GPR119 (0.50) | CHRM2CHRM1CHRM3GPR119KCNK3 | |
| SCHEMBL1029893 | 0.76 | CHRM2 (0.48) | CHRM2CHRM1CHRM3GPR119KCNK3 | |
| SCHEMBL12094684 | 0.76 | CHRM2 (0.45) | CHRM2CHRM1CHRM3GPR119KCNK3 | |
| SCHEMBL20989610 | 0.76 | GPR119 (0.51) | CHRM2CHRM1CHRM3GPR119PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278013-B | 2, 6-disubstituted 1,2, 4-triazine-3, 5-diketone compound and preparation method and application thereof | 昆药集团股份有限公司 | 2022-09-23 | — | — | CN | disclosed |