Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.52 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.47 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.47 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.47 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.47 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.47 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.47 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.47 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.47 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.47 |
| ▸ | CACNA2D3 | Q8IZS8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986381 | 0.83 | CHRM2 (0.44) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL29986931 | 0.83 | ALDH1A1 (0.38) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL5266887 | 0.78 | GPR119 (0.65) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL2776282 | 0.77 | GPR119 (0.64) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL2776764 | 0.77 | GPR119 (0.69) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL1066568 | 0.76 | GPR119 (0.57) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL28660604 | 0.76 | GPR119 (0.53) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL23311676 | 0.75 | GPR119 (0.53) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL3343917 | 0.75 | GPR119 (0.64) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL31403127 | 0.75 | GPR119 (0.50) | GPR119CACNB4CACNA1ACACNA1GCACNG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278013-B | 2, 6-disubstituted 1,2, 4-triazine-3, 5-diketone compound and preparation method and application thereof | 昆药集团股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-113278013-A | 2, 6-disubstituted 1,2, 4-triazine-3, 5-diketone compound and preparation method and application thereof | 昆药集团股份有限公司 | 2021-08-20 | — | — | CN | disclosed |