Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274965 | 0.95 | RAB9A (0.47) | RAB9ARXFP1ALDH1A1KDM4EGAA | |
| SCHEMBL298937 | 0.90 | RAB9A (0.45) | RAB9ARXFP1ALDH1A1KDM4EGAA | |
| SCHEMBL1274616 | 0.88 | RAB9A (0.52) | RAB9ARXFP1ALDH1A1KDM4EGAA | |
| SCHEMBL298774 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL1275432 | 0.85 | CYP1A2 (0.52) | RAB9ARXFP1ALDH1A1KDM4EGAA | |
| SCHEMBL299819 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL13076340 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL17399561 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL299163 | 0.82 | KMT2A (0.60) | ALDH1A1MAPT | |
| SCHEMBL1275752 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427439-A1 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | claimed |