Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31633648 | 0.89 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19RAB9ARXFP1 | |
| SCHEMBL1274616 | 0.88 | RAB9A (0.52) | CYP1A2CYP2C9CYP2C19RAB9ARXFP1 | |
| SCHEMBL299864 | 0.85 | RAB9A (0.49) | CYP1A2CYP2C9CYP2C19RAB9ARXFP1 | |
| SCHEMBL31633646 | 0.85 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL1274965 | 0.83 | RAB9A (0.47) | CYP1A2CYP2C9CYP2C19RAB9ARXFP1 | |
| SCHEMBL31633659 | 0.81 | MAPT (0.59) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL298806 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL31633662 | 0.80 | MAPT (0.47) | RAB9AMAPTKDM4ELMNANPC1 | |
| SCHEMBL14562904 | 0.79 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19RAB9ARXFP1 | |
| SCHEMBL298937 | 0.78 | RAB9A (0.45) | CYP1A2CYP2C9CYP2C19RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153497-A2 | PESTICIDAL CARBOXAMIDES | Bayer Cropscience AG (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-9227923-B2 | Pesticidal carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| US-9227923-B2 | Pesticidal carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| EP-2464624-A2 | PESTICIDAL CARBOXAMIDES | Bayer CropScience AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-20120149910-A1 | Pesticidal Carboxamides | BAYER CROPSCIENCE AG (DE) | 2012-06-14 | — | — | US | disclosed |
| US-20120149910-A1 | Pesticidal Carboxamides | BAYER CROPSCIENCE AG (DE) | 2012-06-14 | — | — | US | disclosed |
| WO-2011018170-A2 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149910-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | CYP1A2 338/4885CYP2C9 258/4885CYP2C19 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.