Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 6/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814436 | 1.00 | DPP8 (0.42) | DPP8DPP9DPP7TRAP1NAMPT | |
| SCHEMBL24814434 | 0.86 | ALDH1A1 (0.47) | GAAKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL29986261 | 0.86 | ALDH1A1 (0.47) | GAAKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL24815667 | 0.83 | ALDH1A1 (0.39) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL24815709 | 0.80 | NAMPT (0.44) | DPP8DPP9DPP7NAMPTMGAM | |
| SCHEMBL29986538 | 0.77 | PKM (0.55) | DPP8DPP9DPP7TRAP1GAA | |
| SCHEMBL24814711 | 0.77 | PKM (0.55) | DPP8DPP9DPP7TRAP1GAA | |
| SCHEMBL29986896 | 0.77 | DPP8 (0.41) | DPP8DPP9DPP7TRAP1NAMPT | |
| SCHEMBL24814392 | 0.77 | DPP8 (0.41) | DPP8DPP9DPP7TRAP1NAMPT | |
| SCHEMBL24816166 | 0.76 | ALDH1A1 (0.39) | GAAKMT2AALDH1A1MEN1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |