Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815800 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL24814430 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL29986546 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL24817130 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL29986910 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL24815673 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL29986247 | 0.80 | TAS1R3 (0.47) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL24816196 | 0.80 | TAS1R3 (0.50) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL24814422 | 0.80 | TAS1R3 (0.47) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL29986069 | 0.80 | TAS1R3 (0.50) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |