Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987355 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL14514562 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL14026154 | 0.79 | MAOB (0.40) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL4014542 | 0.79 | GAA (0.44) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL14191690 | 0.79 | GAA (0.44) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL4014545 | 0.79 | GAA (0.44) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL23829567 | 0.79 | LMNA (0.54) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL16620608 | 0.79 | LMNA (0.54) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL16620607 | 0.79 | LMNA (0.54) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL14191688 | 0.77 | CYP3A4 (0.49) | ALDH1A1LMNAGAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110078675-B | 4-aryl quinazoline compound and preparation method thereof | 郑州大学 | 2022-09-23 | — | — | CN | disclosed |