SCHEMBL16620608

SCHEMBL16620608

CC=Nc1ccccc1C#N

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
ALDH1A1 P00352 4/20 0.54
SMN1; SMN2 Q16637 2/20 0.49
TSHR P16473 2/20 0.45
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
IMPDH2 P12268 2/20 0.36
IMPDH1 P20839 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
HTT P42858 2/20 0.35
GAA P10253 2/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
PDK2 Q15119 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23829567 1.00 LMNA (0.54) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL16620607 1.00 LMNA (0.54) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL29986929 0.79 ALDH1A1 (0.50) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL16620645 0.79 ALDH1A1 (0.50) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL29987355 0.79 ALDH1A1 (0.50) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL14514562 0.79 ALDH1A1 (0.50) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL16620644 0.79 ALDH1A1 (0.50) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL21755864 0.77 CA12 (0.46) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL15497903 0.77 CA12 (0.46) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL11587787 0.76 LMNA (0.75) LMNAALDH1A1SMN1; SMN2TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052531-B1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORP (JP) 2024-07-24 EP disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-11066486-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2021-07-20 US disclosed
US-20200157253-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2020-05-21 US disclosed
US-10590208-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2020-03-17 US disclosed
CN-105814087-B Polymers functionalized with imine compounds containing cyano groups 株式会社普利司通 2017-07-11 CN disclosed
US-20160237179-A1 Polymers Functionalized With Imine Compounds Containing A Cyano Group BRIDGESTONE CORPORATION (JP) 2016-08-18 US disclosed
EP-3052531-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP Bridgestone Corporation (JP) 2016-08-10 EP disclosed
CN-105814087-A Polymers functionalized with imine compounds containing cyano groups 株式会社普利司通 2016-07-27 CN disclosed
WO-2015050947-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2015-04-09 WO disclosed