Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.62 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24817150 | 1.00 | AOC3 (0.62) | AOC3ABHD6GSK3BTMEM97SIGMAR1 | |
| SCHEMBL13063441 | 0.79 | ABHD6 (0.65) | AOC3ABHD6TMEM97SIGMAR1ADRA2A | |
| SCHEMBL14959464 | 0.78 | ABHD6 (0.68) | AOC3ABHD6TMEM97SIGMAR1ADRA2A | |
| SCHEMBL2809581 | 0.75 | ABHD6 (0.67) | AOC3ABHD6TMEM97SIGMAR1ADRA2A | |
| SCHEMBL24815698 | 0.75 | HSD17B10 (0.61) | AOC3ABHD6TMEM97SIGMAR1ADRA2A | |
| SCHEMBL29986948 | 0.75 | HSD17B10 (0.61) | AOC3ABHD6TMEM97SIGMAR1ADRA2A | |
| SCHEMBL13165377 | 0.74 | ABHD6 (0.63) | AOC3ABHD6TMEM97SIGMAR1ADRA2A | |
| SCHEMBL24814718 | 0.74 | AOC3 (0.49) | AOC3ABHD6TMEM97SIGMAR1ADRA2A | |
| SCHEMBL29986210 | 0.74 | AOC3 (0.49) | AOC3ABHD6TMEM97SIGMAR1ADRA2A | |
| SCHEMBL19537529 | 0.74 | TMEM97 (0.78) | ABHD6TMEM97SIGMAR1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |