Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 10/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.58 |
| ▸ | HRH1 | P35367 | 5/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.58 |
| ▸ | HRH2 | P25021 | 4/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
| ▸ | HTR1B | P28222 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | HTR1E | P28566 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14959464 | 0.87 | ABHD6 (0.68) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL12187763 | 0.87 | TMEM97 (0.74) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL19537529 | 0.84 | TMEM97 (0.78) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL2809581 | 0.84 | ABHD6 (0.67) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL13165377 | 0.82 | ABHD6 (0.63) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL20983835 | 0.79 | ABHD6 (1.00) | ABHD6 | |
| SCHEMBL24817150 | 0.79 | AOC3 (0.62) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL29986944 | 0.79 | AOC3 (0.62) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL13619096 | 0.79 | ABHD6 (0.61) | ABHD6TMEM97SIGMAR1HRH1HRH3 | |
| SCHEMBL19537603 | 0.77 | TMEM97 (0.79) | TMEM97SIGMAR1HRH1HRH3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331243-A1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2010-12-30 | — | — | US | disclosed |
| US-7825152-B2 | serine protease inhibitors, for the treatment of hepatitis c virus infections | NOVARTIS AG (CH) | 2010-11-02 | — | — | US | disclosed |
| US-20070286842-A1 | Organic Compounds and Their Uses | NOVARTIS AG (CH) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331243-A1 | ORGANIC COMPOUNDS AND THEIR USES | OAT, OTC, AOX1 | ABHD6 1888/4885TMEM97 2415/4885SIGMAR1 861/4885 |
| US-20070286842-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | ABHD6 1888/4885TMEM97 2415/4885SIGMAR1 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.