Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | TRAP1 | Q12931 | 4/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814455 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24815673 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL29986910 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL29986546 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24817130 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24815800 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL29986727 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24814430 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24814392 | 0.78 | DPP8 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9ADPP8 | |
| SCHEMBL29986896 | 0.78 | DPP8 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9ADPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |