Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 6/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23421620 | 0.99 | FEN1 (0.35) | THRBHSD11B1FEN1TDO2ALOX5AP | |
| SCHEMBL29986640 | 0.99 | FEN1 (0.35) | THRBHSD11B1FEN1TDO2ALOX5AP | |
| SCHEMBL29414843 | 0.96 | FEN1 (0.37) | THRBHSD11B1FEN1ALOX5APMAPT | |
| SCHEMBL22632540 | 0.96 | FEN1 (0.37) | THRBHSD11B1FEN1ALOX5APMAPT | |
| SCHEMBL21749432 | 0.93 | THRA (0.33) | THRBFEN1MAPTTHRA | |
| SCHEMBL31524123 | 0.93 | THRA (0.33) | THRBFEN1MAPTTHRA | |
| SCHEMBL28632953 | 0.85 | THRB (0.33) | THRBHSD11B1MAPTTHRA | |
| SCHEMBL30075040 | 0.84 | THRB (0.35) | THRBHSD11B1THRA | |
| SCHEMBL24032513 | 0.83 | MAPT (0.33) | MAPT | |
| SCHEMBL23260087 | 0.82 | MAPT (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454069-B | 1,2, 4-Triazine-3, 5-dione compound, and preparation method and application thereof | 昆药集团股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-113278013-B | 2, 6-disubstituted 1,2, 4-triazine-3, 5-diketone compound and preparation method and application thereof | 昆药集团股份有限公司 | 2022-09-23 | — | — | CN | disclosed |