Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 4/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | RXRB | P28702 | 2/20 | 0.31 |
| ▸ | RXRG | P48443 | 2/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27077732 | 0.89 | NPC1 (0.33) | NPC1F2RL1 | |
| SCHEMBL27077756 | 0.85 | NPC1 (0.31) | NPC1 | |
| SCHEMBL27077669 | 0.84 | KDM4E (0.33) | NPC1F2RL1S1PR1PTGER1 | |
| SCHEMBL29987696 | 0.83 | NPC1 (0.41) | NPC1 | |
| SCHEMBL27077783 | 0.82 | F2RL1 (0.32) | NPC1F2RL1 | |
| SCHEMBL27077653 | 0.81 | NPC1 (0.31) | NPC1 | |
| SCHEMBL27435461 | 0.80 | — | — | |
| SCHEMBL27077755 | 0.79 | NPC1 (0.33) | NPC1S1PR1 | |
| SCHEMBL31104326 | 0.70 | ALDH1A1 (0.36) | NPC1F2RL1S1PR1 | |
| SCHEMBL21521058 | 0.69 | HTT (0.49) | NPC1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313300-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022207752-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2022-10-06 | — | — | WO | disclosed |