Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27077653 | 0.90 | NPC1 (0.31) | NPC1 | |
| SCHEMBL27077732 | 0.85 | NPC1 (0.33) | F2RL1NPC1 | |
| SCHEMBL29987343 | 0.82 | NPC1 (0.34) | F2RL1NPC1 | |
| SCHEMBL27077755 | 0.82 | NPC1 (0.33) | NPC1 | |
| SCHEMBL27077756 | 0.80 | NPC1 (0.31) | NPC1 | |
| SCHEMBL27077669 | 0.77 | KDM4E (0.33) | F2RL1NPC1 | |
| SCHEMBL27435461 | 0.77 | — | — | |
| SCHEMBL31104205 | 0.73 | ALDH1A1 (0.33) | F2RL1NPC1 | |
| SCHEMBL31103949 | 0.71 | ALDH1A1 (0.33) | F2RL1NPC1 | |
| SCHEMBL21521058 | 0.71 | HTT (0.49) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-07-04 | — | — | US | disclosed |
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-07-04 | — | — | US | disclosed |
| EP-4313300-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-02-07 | — | — | EP | disclosed |
| CN-117460723-A | Pharmaceutical compounds | 杜克街生物有限公司 | 2024-01-26 | — | — | CN | disclosed |
| WO-2022207752-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2022-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | F11, F12, ZYX | F2RL1 1256/4885NPC1 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.