Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 9/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 8/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988266 | 0.89 | ATF4 (0.57) | ATF4KCNH2 | |
| SCHEMBL29987802 | 0.80 | ATF4 (0.48) | ATF4KCNH2 | |
| SCHEMBL24998294 | 0.79 | CYP3A4 (0.45) | ATF4PTGESTP53MAPTRXFP1 | |
| SCHEMBL29988262 | 0.79 | ATF4 (0.44) | ATF4 | |
| SCHEMBL24997345 | 0.78 | ATF4 (0.43) | ATF4PTGESPTGS2 | |
| SCHEMBL29988078 | 0.78 | RAB9A (0.47) | PTGESPTGS2MAPT | |
| SCHEMBL24997331 | 0.77 | MEN1 (0.42) | ATF4PTGESPTGS2 | |
| SCHEMBL29987826 | 0.77 | CASP3 (0.43) | ATF4 | |
| SCHEMBL29988220 | 0.77 | CASP3 (0.43) | ATF4 | |
| SCHEMBL29988086 | 0.77 | CASP3 (0.43) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212902-A1 | MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY | ALTOS LABS, INC. (US) | 2022-10-06 | — | — | WO | disclosed |