Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27077700 | 0.95 | ALDH1A1 (0.47) | ALDH1A1CYP3A4USP2MAPTLMNA | |
| SCHEMBL27077720 | 0.89 | LMNA (0.44) | ALDH1A1CYP3A4USP2MAPTLMNA | |
| SCHEMBL27077745 | 0.82 | ALDH1A1 (0.45) | ALDH1A1CYP3A4USP2MAPTLMNA | |
| SCHEMBL21809966 | 0.74 | KMT2A (0.44) | ALDH1A1CYP3A4USP2MAPTLMNA | |
| SCHEMBL23123688 | 0.72 | CYP3A4 (0.37) | ALDH1A1CYP3A4USP2MAPTLMNA | |
| SCHEMBL24937256 | 0.72 | SMN1; SMN2 (0.41) | ALDH1A1CYP3A4USP2MAPTLMNA | |
| SCHEMBL27077666 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNANPSR1GAA | |
| SCHEMBL23123184 | 0.69 | CYP3A4 (0.42) | ALDH1A1CYP3A4USP2MAPTLMNA | |
| SCHEMBL11212558 | 0.68 | KMT2A (0.50) | ALDH1A1CYP3A4USP2MAPTLMNA | |
| SCHEMBL19842214 | 0.66 | ALDH1A1 (0.42) | ALDH1A1CYP3A4USP2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313300-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022207752-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2022-10-06 | — | — | WO | disclosed |