Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988060 | 0.82 | RAB9A (0.63) | KDM4ERAB9ANPC1MAPTUSP2 | |
| SCHEMBL21384357 | 0.78 | RAB9A (0.57) | KDM4ERAB9ANPC1USP2POLB | |
| SCHEMBL25961399 | 0.78 | RAB9A (0.68) | KDM4ERAB9ANPC1TSHRHSD17B10 | |
| SCHEMBL1440788 | 0.78 | ALDH1A1 (0.53) | KDM4ERAB9ANPC1MAPTTSHR | |
| SCHEMBL2351379 | 0.77 | TSHR (0.79) | KDM4ENPC1MAPTTSHRHSD17B10 | |
| SCHEMBL2032657 | 0.77 | PTGES (0.60) | KDM4EMAPTTSHRHSD17B10ALOX12 | |
| SCHEMBL21384509 | 0.76 | RAB9A (0.68) | KDM4ERAB9ANPC1TSHRHSD17B10 | |
| SCHEMBL408423 | 0.75 | ALDH1A1 (0.50) | KDM4ERAB9ANPC1MAPTTSHR | |
| SCHEMBL18711352 | 0.75 | RAB9A (0.63) | KDM4ERAB9ANPC1ALOX12USP2 | |
| SCHEMBL2026608 | 0.75 | PTGES (0.62) | KDM4EMAPTTSHRHSD17B10ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212902-A1 | MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY | ALTOS LABS, INC. (US) | 2022-10-06 | — | — | WO | disclosed |