Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10329425 | 1.00 | LMNA (0.50) | LMNAMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL4838298 | 0.82 | FAAH (0.45) | ALDH1A1HPGDKMT2AFAAHAOC3 | |
| SCHEMBL17084221 | 0.81 | FAAH (0.64) | KMT2AFAAHMEN1CRHBPCRHR2 | |
| SCHEMBL71165 | 0.81 | FAAH (0.64) | KMT2AFAAHMEN1CRHBPCRHR2 | |
| SCHEMBL4838409 | 0.81 | FAAH (0.64) | KMT2AFAAHMEN1CRHBPCRHR2 | |
| SCHEMBL8879105 | 0.80 | KMT2A (0.43) | LMNAMAPK1KDM4EKMT2AFAAH | |
| SCHEMBL10329424 | 0.80 | ALDH1A1 (0.46) | LMNAKDM4EALDH1A1KMT2AFAAH | |
| SCHEMBL13357533 | 0.80 | KMT2A (0.43) | LMNAMAPK1KDM4EKMT2AFAAH | |
| SCHEMBL8411090 | 0.80 | FAAH (0.40) | LMNAMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL6164408 | 0.79 | SRC (0.44) | KDM4EKMT2AFAAHMEN1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214964-A2 | SELECTIVE CONNEXIN HEMICHANNEL BLOCKERS AS THERAPEUTIC COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY DISEASES | CONNECTOMICA SPA. (CL) | 2022-10-13 | — | — | WO | disclosed |