SCHEMBL29989707

SCHEMBL29989707

Clc1ncnc2c1oc1ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 1.00
ALDH1A1 P00352 9/20 0.67
LMNA P02545 4/20 0.67
KMT2A Q03164 4/20 0.67
LIMK1 P53667 1/20 0.67
GPR55 Q9Y2T6 1/20 0.67
MAPT P10636 3/20 0.61
HPGD P15428 7/20 0.59
NPC1 O15118 4/20 0.59
RAB9A P51151 4/20 0.59
TSHR P16473 3/20 0.58
HSD17B10 Q99714 3/20 0.58
KDM4E B2RXH2 3/20 0.58
CASP3 P42574 2/20 0.58
SENP7 Q9BQF6 2/20 0.58
PPARG P37231 2/20 0.58
NCOA1 Q15788 2/20 0.58
TDP1 Q9NUW8 1/20 0.58
NCOA2 Q15596 1/20 0.58
MEN1 O00255 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4539658 1.00 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1
SCHEMBL27164742 0.86 SMN1; SMN2 (0.74) SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1
SCHEMBL25485328 0.81 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1
SCHEMBL23610616 0.80 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1
SCHEMBL4594832 0.80 ALDH1A1 (1.00) SMN1; SMN2ALDH1A1LMNAKMT2AGPR55
SCHEMBL16406269 0.80 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1
SCHEMBL22872914 0.80 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1
SCHEMBL4436186 0.80 LIMK1 (1.00) SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1
SCHEMBL20502082 0.80 SMN1; SMN2 (0.66) SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1
SCHEMBL30080988 0.80 SMN1; SMN2 (0.66) SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111354874-B Light emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2023-07-04 CN disclosed
CN-116333001-A Organometallic compound and organic light emitting diode including the same 乐金显示有限公司 2023-06-27 CN disclosed
CN-111129325-B Light emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2023-06-09 CN disclosed
CN-111341927-B Light emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2023-06-09 CN disclosed
CN-115103845-A Organic compound, light-emitting device, electronic apparatus, light-emitting device, and lighting device 株式会社半导体能源研究所 2022-09-23 CN disclosed