Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | CASP3 | P42574 | 2/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989707 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1 | |
| SCHEMBL27164742 | 0.86 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1 | |
| SCHEMBL25485328 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1 | |
| SCHEMBL23610616 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1 | |
| SCHEMBL4594832 | 0.80 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1LMNAKMT2AGPR55 | |
| SCHEMBL16406269 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1 | |
| SCHEMBL22872914 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1 | |
| SCHEMBL4436186 | 0.80 | LIMK1 (1.00) | SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1 | |
| SCHEMBL20502082 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1 | |
| SCHEMBL30080988 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1LMNAKMT2ALIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630759-B1 | COMPOUNDS USEFUL AS ION CHANNEL INHIBITORS FOR THE TREATMENT OF CANCER | CENTRE NAT RECH SCIENT (FR) | 2024-05-01 | — | — | EP | disclosed |
| US-11932638-B2 | Ion channel inhibitor compounds for cancer treatment | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE (FR) | 2024-03-19 | — | — | US | disclosed |
| EP-4061818-B1 | MACROCYCLIC PEPTIDES AS PD-L1 INHIBITORS AND IMMUNOMODULATORS FOR THE TREATMENT OF CANCER AND INFECTIOUS DISEASES | BRISTOL MYERS SQUIBB CO (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20230269954-A1 | Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO. LTD. (JP) | 2023-08-24 | — | — | US | disclosed |
| US-20230210005-A1 | Light-Emitting Element, Compound, Organic Compound, Display Module, Lighting Module, Light-Emitting Device, Display Device, Lighting Device, and Electronic Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2023-06-29 | — | — | US | disclosed |
| US-20230210005-A1 | Light-Emitting Element, Compound, Organic Compound, Display Module, Lighting Module, Light-Emitting Device, Display Device, Lighting Device, and Electronic Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2023-06-29 | — | — | US | disclosed |
| CN-116333001-A | Organometallic compound and organic light emitting diode including the same | 乐金显示有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20230129057-A1 | Organic Compound, Light-Emitting Device, Electronic Device, Electronic Apparatus, Light-Emitting Apparatus, and Lighting Apparatus | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2023-04-27 | — | — | US | disclosed |
| US-11600789-B2 | Light-emitting element, compound, organic compound, display module, lighting module, light-emitting device, display device, lighting device, and electronic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2023-03-07 | — | — | US | disclosed |
| US-20230022400-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-01-26 | — | — | US | disclosed |
| US-20130302303-A1 | PROTEIN KINASE INHIBITORS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2013-11-14 | — | — | US | disclosed |
| WO-2009081222-A1 | SUBSTITUTED TRICYCLIC PYRIDINE OR PYRIMIDINE VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-02 | — | — | WO | disclosed |
| US-20090143399-A1 | Protein Kinase Inhibitors | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090099165-A1 | Protein Kinase Inhibitors | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2009-04-16 | — | — | US | disclosed |
| US-20080051414-A1 | Protein Kinase Inhibitors | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2008-02-28 | — | — | US | disclosed |
| US-7326712-B2 | Substituted tricyclic compounds as protein kinase inhibitors | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2008-02-05 | — | — | US | disclosed |
| US-7312226-B2 | Substituted tricyclic compounds as protein kinase inhibitors | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2007-12-25 | — | — | US | disclosed |
| US-6596726-B1 | Method of inhibiting epidermal growth factor by treating, with an effective inhibiting amount, a mammal, in need thereof inhibit the epidermal growth factor receptor and related receptors and, in particular, their tyrosine kinase enzyme | WARNER LAMBERT COMPANY | 2003-07-22 | — | — | US | disclosed |
| EP-0741711-A1 | TRICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY | WARNER-LAMBERT COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995019970-A1 | TRICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY | WARNER-LAMBERT COMPANY (US) | 1995-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099165-A1 | Protein Kinase Inhibitors | CDK2, MAP3K1, MAP3K2 | SMN1; SMN2 3186/4885ALDH1A1 2994/4885LMNA 1805/4885 |
| US-20230022400-A1 | IMMUNOMODULATORS | CD274, PDCD1LG2, PDCD1 | SMN1; SMN2 4465/4885ALDH1A1 1602/4885LMNA 4793/4885 |
| US-20230129057-A1 | Organic Compound, Light-Emitting Device, Electronic Device, Electronic Apparatus, Light-Emitting Apparatus, and Lighting Apparatus | TEAD1, GTF2F1, GTF2F2 | SMN1; SMN2 4507/4885ALDH1A1 127/4885LMNA 3383/4885 |
| US-11600789-B2 | Light-emitting element, compound, organic compound, display module, lighting module, light-emitting device, display device, lighting device, and electronic device | TPMT, DPYD, DHODH | SMN1; SMN2 2757/4885ALDH1A1 122/4885LMNA 4035/4885 |
| US-20230210005-A1 | Light-Emitting Element, Compound, Organic Compound, Display Module, Lighting Module, Light-Emitting Device, Display Device, Lighting Device, and Electronic Device | TPMT, DPYD, DHODH | SMN1; SMN2 2757/4885ALDH1A1 122/4885LMNA 4035/4885 |
| US-11932638-B2 | Ion channel inhibitor compounds for cancer treatment | CACNA1E, KCNA1, KCNT1 | SMN1; SMN2 3797/4885ALDH1A1 680/4885LMNA 2341/4885 |
| US-20130302303-A1 | PROTEIN KINASE INHIBITORS | CDK2, MAP3K1, MAP3K2 | SMN1; SMN2 3186/4885ALDH1A1 2994/4885LMNA 1805/4885 |
| US-20080051414-A1 | Protein Kinase Inhibitors | CDK2, MAP3K1, MAP3K2 | SMN1; SMN2 3186/4885ALDH1A1 2994/4885LMNA 1805/4885 |
| US-20090143399-A1 | Protein Kinase Inhibitors | CDK2, MAP3K1, MAP3K2 | SMN1; SMN2 3186/4885ALDH1A1 2994/4885LMNA 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.