SCHEMBL4594832

SCHEMBL4594832

Clc1ccc2oc3c(Cl)ncnc3c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 1.00
LMNA P02545 1/20 1.00
KMT2A Q03164 1/20 1.00
GPR55 Q9Y2T6 1/20 1.00
SMN1; SMN2 Q16637 1/20 0.67
CDC7 O00311 1/20 0.59
DYRK3 O43781 1/20 0.59
IGF1R P08069 1/20 0.59
PIM1 P11309 1/20 0.59
CLK2 P49760 1/20 0.59
GSK3A P49840 1/20 0.59
GSK3B P49841 1/20 0.59
CSNK2A1 P68400 1/20 0.59
DYRK1A Q13627 1/20 0.59
PKN2 Q16513 1/20 0.59
PIM3 Q86V86 1/20 0.59
CLK4 Q9HAZ1 1/20 0.59
PIM2 Q9P1W9 1/20 0.59
HRH4 Q9H3N8 14/20 0.58
AHR P35869 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31695336 0.85 ALDH1A1 (0.73) ALDH1A1LMNAKMT2AGPR55SMN1; SMN2
SCHEMBL18496512 0.83 ALDH1A1 (0.71) ALDH1A1LMNAKMT2AGPR55SMN1; SMN2
SCHEMBL4594004 0.83 ALDH1A1 (0.71) ALDH1A1LMNAKMT2AGPR55SMN1; SMN2
SCHEMBL29989707 0.80 SMN1; SMN2 (1.00) ALDH1A1LMNAKMT2AGPR55SMN1; SMN2
SCHEMBL4539658 0.80 SMN1; SMN2 (1.00) ALDH1A1LMNAKMT2AGPR55SMN1; SMN2
SCHEMBL2494411 0.79 KMT2A (0.66) ALDH1A1LMNAKMT2AGPR55CDC7
SCHEMBL30117918 0.79 KMT2A (0.66) ALDH1A1LMNAKMT2AGPR55CDC7
SCHEMBL23610616 0.79 SMN1; SMN2 (0.67) ALDH1A1LMNAKMT2AGPR55SMN1; SMN2
SCHEMBL4593656 0.79 ALDH1A1 (0.65) ALDH1A1LMNAKMT2AGPR55SMN1; SMN2
SCHEMBL27164742 0.78 SMN1; SMN2 (0.74) ALDH1A1LMNAKMT2AGPR55SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313568-A1 Organic Compound, Mixture Thereof, And Method For Synthesizing Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2025-10-09 US disclosed
US-20250204248-A1 Organic Compound And Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2025-06-19 US disclosed
CN-120157700-A Organic compound and light-emitting device 株式会社半导体能源研究所 2025-06-17 CN disclosed
US-20240373748-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-11-07 US disclosed
US-12043624-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-23 US disclosed
US-12043624-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-23 US disclosed
US-12043624-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-23 US disclosed
US-12029118-B2 Organic compound, light-emitting device, light-emitting apparatus, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-02 US disclosed
US-12029118-B2 Organic compound, light-emitting device, light-emitting apparatus, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-02 US disclosed
US-12029118-B2 Organic compound, light-emitting device, light-emitting apparatus, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-02 US disclosed
US-20080261946-A1 Pyrimidine Compounds for the Treatment of Inflammatory Disorders CELLZOME (UK) LTD. (GB) 2008-10-23 US disclosed
EP-1945646-A1 PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS Cellzome (UK) Ltd. (GB) 2008-07-23 EP disclosed
EP-1812113-A1 PYRIMIDINE COMPOUNDS AS HISTAMINE MODULATORS Argenta Discovery Limited (GB) 2007-08-01 EP disclosed
EP-1776982-A1 Pyrimidine compounds as histamine modulators Argenta Discovery Limited (GB) 2007-04-25 EP disclosed
EP-1776982-A1 Pyrimidine compounds as histamine modulators Argenta Discovery Limited (GB) 2007-04-25 EP disclosed
WO-2007039467-A1 PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS CELLZOME (UK) LTD. (GB) 2007-04-12 WO disclosed
WO-2007039467-A1 PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS CELLZOME (UK) LTD. (GB) 2007-04-12 WO disclosed
EP-1767537-A1 Pyrimidine compounds for the treatment of inflammatory disorders Cellzome (UK) Ltd. (GB) 2007-03-28 EP disclosed
EP-1767537-A1 Pyrimidine compounds for the treatment of inflammatory disorders Cellzome (UK) Ltd. (GB) 2007-03-28 EP disclosed
WO-2006050965-A1 PYRIMIDINE COMPOUNDS AS HISTAMINE MODULATORS ARGENTA DISCOVERY LTD (GB) 2006-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043624-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device CCNE2, NFE2L2, AOX1 ALDH1A1 134/4885LMNA 3438/4885KMT2A 1223/4885
US-12029118-B2 Organic compound, light-emitting device, light-emitting apparatus, electronic device and lighting device TPMT, CYP1A1, CYP1B1 ALDH1A1 31/4885LMNA 2796/4885KMT2A 1994/4885
US-20080261946-A1 Pyrimidine Compounds for the Treatment of Inflammatory Disorders HRH4, HRH3, HRH2 ALDH1A1 1823/4885LMNA 4565/4885KMT2A 1030/4885
US-20250313568-A1 Organic Compound, Mixture Thereof, And Method For Synthesizing Organic Compound XDH, BMP4, ODC1 ALDH1A1 3319/4885LMNA 3962/4885KMT2A 3749/4885
US-20240373748-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device TPMT, CYP1A1, CYP3A4 ALDH1A1 34/4885LMNA 2910/4885KMT2A 2264/4885
US-20250204248-A1 Organic Compound And Light-Emitting Device TPMT, PAICS, TYMS ALDH1A1 557/4885LMNA 3924/4885KMT2A 2395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.