Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 5/20 | 0.60 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.60 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PRCP | P42785 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29991483 | 0.98 | GNAI3 (0.57) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL4484094 | 0.94 | GAA (0.58) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL8487311 | 0.92 | ACHE (0.57) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL29990844 | 0.87 | EPHX1 (0.50) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL6695746 | 0.87 | GAA (0.60) | EPHX1GAAPRCPBCHENAAA | |
| SCHEMBL8482146 | 0.86 | TDP1 (0.45) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL14703637 | 0.86 | EPHX1 (0.62) | EPHX1GAANAAA | |
| SCHEMBL3647096 | 0.85 | GAA (0.56) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL21059247 | 0.84 | EPHX1 (0.65) | EPHX1GAANAAA | |
| SCHEMBL15975473 | 0.84 | EPHX1 (0.65) | EPHX1GAANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013067-A1 | 4-SUBSTITUTED PIPERIDINECARBOXYLIC ACID ESTERS: INHIBITION OF CHOLESTEROL ABSORPTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5169844-A | Enzyme inhibitor, anticholesterol and antilipemic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |