SCHEMBL29992425

SCHEMBL29992425

O=C1c2cc(Br)ccc2S(=O)(=O)c2cc(Cl)ccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.43
CHEK1 O14757 3/20 0.41
DAPK3 O43293 1/20 0.41
MAP4K4 O95819 1/20 0.41
RET P07949 1/20 0.41
PIM1 P11309 1/20 0.41
LTK P29376 1/20 0.41
GRK5 P34947 1/20 0.41
CSNK1A1 P48729 1/20 0.41
CDK8 P49336 1/20 0.41
PRKX P51817 1/20 0.41
LIMK1 P53667 1/20 0.41
CDK5 Q00535 1/20 0.41
ACVR1 Q04771 1/20 0.41
PTK2 Q05397 1/20 0.41
TYRO3 Q06418 1/20 0.41
PRKAA1 Q13131 1/20 0.41
DYRK1A Q13627 1/20 0.41
NTRK3 Q16288 1/20 0.41
LRRK2 Q5S007 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28402336 1.00 S100A4 (0.43) S100A4CHEK1DAPK3MAP4K4RET
SCHEMBL20389951 0.89 S100A4 (0.50) S100A4CHEK1BCL2MCL1MEN1
SCHEMBL18267527 0.85 S100A4 (0.52) S100A4CHEK1BCL2MCL1L3MBTL1
SCHEMBL20389948 0.81 MAOA (0.52) S100A4CHEK1BCL2MCL1MAOA
SCHEMBL20382197 0.81 S100A4 (0.52) S100A4CHEK1BCL2MCL1MEN1
SCHEMBL17954672 0.80 MAOA (0.54) S100A4CHEK1MEN1KMT2AL3MBTL1
SCHEMBL5800591 0.80 CHEK1 (0.59) S100A4CHEK1MEN1KMT2AL3MBTL1
SCHEMBL10945035 0.77 MAOA (0.57) S100A4CHEK1DAPK3MAP4K4RET
SCHEMBL24730389 0.76 BCL2 (0.57) S100A4BCL2MCL1L3MBTL1PTPRC
SCHEMBL21832063 0.76 S100A4 (0.45) S100A4CHEK1BCL2MCL1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233914-B Star-shaped thermal activation delayed fluorescent material, electronic device and application thereof 深圳大学 2022-12-06 CN disclosed