Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | GPR3 | P46089 | 1/20 | 0.52 |
| ▸ | S100A4 | P26447 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24155578 | 0.91 | GPR3 (0.64) | CHEK1MEN1KMT2AL3MBTL1MAOA | |
| SCHEMBL10945035 | 0.89 | MAOA (0.57) | CHEK1MEN1KMT2AL3MBTL1MAOA | |
| SCHEMBL31472931 | 0.82 | GPR3 (0.75) | CHEK1MEN1KMT2AL3MBTL1MAOA | |
| SCHEMBL472539 | 0.82 | GPR3 (0.75) | CHEK1MEN1KMT2AL3MBTL1MAOA | |
| SCHEMBL29368441 | 0.82 | GPR3 (0.75) | CHEK1MEN1KMT2AL3MBTL1MAOA | |
| SCHEMBL31619304 | 0.80 | CHEK1 (0.48) | CHEK1GPR3S100A4ALDH1A1HPGD | |
| SCHEMBL29992425 | 0.80 | S100A4 (0.43) | CHEK1MEN1KMT2AL3MBTL1MAOA | |
| SCHEMBL28402336 | 0.80 | S100A4 (0.43) | CHEK1MEN1KMT2AL3MBTL1MAOA | |
| SCHEMBL12796758 | 0.79 | CHEK1 (0.59) | CHEK1MEN1KMT2AL3MBTL1MAOA | |
| SCHEMBL16900704 | 0.79 | MEN1 (0.62) | CHEK1MEN1KMT2AL3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060774-A2 | AGENTS THAT INHIBIT FLAVIVIRUS REPLICATION AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-06-08 | — | — | WO | disclosed |