Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.59 |
| ▸ | DNPH1 | O43598 | 9/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511838 | 0.90 | TAS1R3 (0.71) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 | |
| SCHEMBL939116 | 0.90 | TAS1R3 (0.71) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 | |
| SCHEMBL29941361 | 0.83 | P2RX3 (0.71) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 | |
| SCHEMBL29511839 | 0.83 | P2RX3 (0.71) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 | |
| SCHEMBL14874567 | 0.83 | TAS1R3 (0.67) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 | |
| SCHEMBL15248805 | 0.82 | TAS1R3 (0.66) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 | |
| SCHEMBL12304459 | 0.82 | TAS1R3 (0.66) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 | |
| SCHEMBL15071490 | 0.82 | TAS1R3 (0.66) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 | |
| Adenosine Phosphate SCHEMBL18287224 | 0.76 | DNPH1 (0.68) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 | |
| SCHEMBL29729918 | 0.75 | TAS1R3 (0.67) | TAS1R3TAS1R1DNPH1PRKAB2TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119220474-B | Escherichia coli genetically engineered bacterium for producing L-histidine through fermentation, method and application | 天津科技大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119220474-A | Escherichia coli genetically engineered bacterium for producing L-histidine through fermentation, method and application | 天津科技大学 | 2024-12-31 | — | — | CN | claimed |
| CN-119220474-B | Escherichia coli genetically engineered bacterium for producing L-histidine through fermentation, method and application | 天津科技大学 | 2025-02-25 | — | — | CN | disclosed |
| US-20250037787-A1 | CONCENTRATION BOUNDS IN LARGE NETWORKS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-01-30 | — | — | US | disclosed |
| CN-119220474-A | Escherichia coli genetically engineered bacterium for producing L-histidine through fermentation, method and application | 天津科技大学 | 2024-12-31 | — | — | CN | disclosed |
| US-12031139-B2 | Stable transformation of a population and a method of biocontainment using haploinsufficiency and underdominance principles | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2024-07-09 | — | — | US | disclosed |
| US-20240124907-A1 | Engineered Biosynthetic Pathways for Production of Histamine by Fermentation | ZYMERGEN INC. (US) | 2024-04-18 | — | — | US | disclosed |
| US-11739355-B2 | Engineered biosynthetic pathways for production of histamine by fermentation | ZYMERGEN INC. (US) | 2023-08-29 | — | — | US | disclosed |
| US-20230065419-A1 | ENHANCED PRODUCTION OF HISTIDINE, PURINE PATHWAY METABOLITES, AND PLASMID DNA | GINKGO BIOWORKS, INC. (US) | 2023-03-02 | — | — | US | disclosed |
| EP-4077650-A1 | ENHANCED PRODUCTION OF HISTIDINE, PURINE PATHWAY METABOLITES, AND PLASMID DNA | Ginkgo Bioworks, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-115175994-A | Enhanced production of histidine, purine pathway metabolites and plasmid DNA | 银杏生物制品公司 | 2022-10-11 | — | — | CN | disclosed |