SCHEMBL29993400

SCHEMBL29993400

Nc1ccccc1C(=O)c1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
HDAC3 O15379 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56
HDAC5 Q9UQL6 1/20 0.56
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
MAPT P10636 2/20 0.53
GAA P10253 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
LMNA P02545 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
P4HTM Q9NXG6 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL367924 1.00 KMT2A (0.56) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL16211860 0.84 NAPRT (0.59) KMT2ACES2CES1L3MBTL1LMNA
Anthranilamide SCHEMBL3890723 0.82 HDAC3 (0.53) KMT2AHDAC3HDAC4HDAC1HDAC7
Anthranilic Acid SCHEMBL11343850 0.82 L3MBTL1 (0.69) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL6122369 0.82 KEAP1 (0.53) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL12703046 0.82 KMT2A (0.49) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL31366584 0.82 RECQL (0.58) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL342047 0.82 RECQL (0.58) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL29143025 0.82 RAB9A (0.52) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL29488296 0.82 MAPT (0.59) KMT2AHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798149-A Preparation method of 2- (2-amino-5-bromo-benzoyl) pyridine 宜昌天睿生物医药有限责任公司 2025-04-11 CN claimed
CN-119798149-A Preparation method of 2- (2-amino-5-bromo-benzoyl) pyridine 宜昌天睿生物医药有限责任公司 2025-04-11 CN disclosed
CN-119798149-A Preparation method of 2- (2-amino-5-bromo-benzoyl) pyridine 宜昌天睿生物医药有限责任公司 2025-04-11 CN disclosed
CN-115947690-B Preparation method of indazole molecular building block and application of indazole molecular building block in drug synthesis 安徽医科大学 2025-04-08 CN disclosed
CN-115322144-B Preparation method of 2- (2-amino-5-bromo-benzoyl) pyridine 上海药坦药物研究开发有限公司 2024-05-24 CN disclosed
CN-117447393-A Preparation method of intermediate of Rayleigh Malun 浙江雅辰药物科技股份有限公司 2024-01-26 CN disclosed
CN-115947690-A Preparation method of indazole molecular building block and application of building block in drug synthesis 安徽医科大学 2023-04-11 CN disclosed
CN-115322144-A Preparation method of 2- (2-amino-5-bromo-benzoyl) pyridine 上海药坦药物研究开发有限公司 2022-11-11 CN disclosed