Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993809 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL20155400 | 0.71 | PDE4D (0.39) | LRRK2PDE4DPTPN11 | |
| SCHEMBL26921636 | 0.70 | PTPN11 (0.35) | LRRK2PDE4DPTPN11 | |
| SCHEMBL17404485 | 0.67 | KDM5A (0.43) | — | |
| SCHEMBL26921676 | 0.64 | PTPN11 (0.33) | PTPN11 | |
| SCHEMBL476839 | 0.64 | HPGD (0.37) | — | |
| SCHEMBL28596096 | 0.63 | IRAK4 (0.36) | LRRK2 | |
| SCHEMBL29303422 | 0.62 | HDAC8 (0.34) | PTPN11 | |
| SCHEMBL29304924 | 0.62 | ALDH1A1 (0.39) | PTPN11 | |
| SCHEMBL29175942 | 0.61 | LRRK2 (0.35) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237178-A1 | BICYCLIC HETEROARYL DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2022-11-17 | — | — | WO | disclosed |