Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474592 | 0.83 | PRMT5 (0.41) | SLC9A1KEAP1SMN1; SMN2RECQLPRMT5 | |
| SCHEMBL28161565 | 0.73 | PDPK1 (0.44) | SLC9A1KEAP1SMN1; SMN2RECQLPRMT5 | |
| SCHEMBL29993730 | 0.71 | MAPK13 (0.35) | SMN1; SMN2 | |
| SCHEMBL19489400 | 0.70 | PTPN11 (0.33) | — | |
| SCHEMBL13067164 | 0.67 | ESR2 (0.49) | SLC9A1KEAP1SMN1; SMN2RECQL | |
| SCHEMBL13106159 | 0.67 | PARP1 (0.41) | SLC9A1KEAP1PRMT5 | |
| SCHEMBL22199110 | 0.67 | RECQL (0.36) | SMN1; SMN2RECQL | |
| SCHEMBL21631683 | 0.66 | PTPN11 (0.33) | — | |
| SCHEMBL21653695 | 0.66 | PTPN11 (0.35) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL28701856 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237178-A1 | BICYCLIC HETEROARYL DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2022-11-17 | — | — | WO | disclosed |