Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | UNG | P13051 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196036 | 1.00 | DRD2 (0.42) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL2281435 | 0.93 | ALDH1A1 (0.42) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL6159034 | 0.80 | SRC (0.42) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL6228972 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2CYP2A6KDM4EHSD17B10 | |
| SCHEMBL6517741 | 0.77 | MEN1 (0.34) | ALDH1A1SMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL4576244 | 0.75 | TP53 (0.42) | DRD3ALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL20083395 | 0.74 | TAAR1 (0.44) | ALDH1A1SMN1; SMN2HTTLMNAATM | |
| SCHEMBL1909839 | 0.74 | ALDH1A1 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL11792550 | 0.74 | ALDH1A1 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL3437970 | 0.73 | DRD2 (0.58) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335050-A | Compounds and compositions for treating skin conditions | 卡玛瑞制药有限公司 | 2022-11-11 | — | — | CN | disclosed |