Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517741 | 0.83 | MEN1 (0.34) | ALDH1A1TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL2281435 | 0.81 | ALDH1A1 (0.42) | TDP1ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL4140760 | 0.79 | TP53 (0.44) | TP53TDP1ALDH1A1TSHR | |
| SCHEMBL1499389 | 0.79 | TSHR (0.48) | TP53TDP1ALDH1A1TSHRDRD3 | |
| SCHEMBL28756738 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ACYP2C19SMN1; SMN2 | |
| SCHEMBL4575908 | 0.76 | ALDH1A1 (0.48) | TDP1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6196036 | 0.75 | DRD2 (0.42) | TDP1ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL29995306 | 0.75 | DRD2 (0.42) | TDP1ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL2281217 | 0.75 | ENPP2 (0.46) | — | |
| SCHEMBL2453903 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763978-B2 | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable covalent bonds and their use in treating celiac disease | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2017-09-19 | — | — | US | disclosed |
| US-20150064131-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE | VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) | 2015-03-05 | — | — | US | disclosed |
| US-8883133-B2 | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable their use in treating celiac disease | VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) | 2014-11-11 | — | — | US | disclosed |
| US-8784792-B2 | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable covalent bonds and their use in treating celiac disease | Valorization-Recherche Limited Partnership (CA) | 2014-07-22 | — | — | US | disclosed |
| US-8304171-B2 | Plate making method of lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-11-06 | — | — | US | disclosed |
| US-20120244105-A1 | Pharmaceutical Compositions Comprising Polymeric Binders with Non-Hydrolysable Covalent Bonds and Their Use in Treating Celiac Disease | VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) | 2012-09-27 | — | — | US | disclosed |
| US-20100075260-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20100075260-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20080254099-A1 | Such as high molecular weight copolymer of hydroxyethyl methacrylate and 4-styrene sulfonic acid sodium salt; decreasing interaction of gluten or peptide degradation products with intestinal tract; breads | VALORISATION-RECHERCHE, LIMITED (CA) | 2008-10-16 | — | — | US | disclosed |
| EP-1948201-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE | UNIVERSITE DE MONTREAL (CA) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007053935-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE | UNIVERSITE DE MONTREAL (CA) | 2007-05-18 | — | — | WO | disclosed |
| US-5428171-A | Leukotrienes antagonist; antiasthmatic, antiallergic, anti-inflammatory and cytoprotective agent | MERCK FROSST CANADA, INC. (CA) | 1995-06-27 | — | — | US | disclosed |
| US-4851409-A | LEUKOTRIENE ANTAGONIST, ANTIASTHMA, ANTIALLERGEN, ANTIINFLAMMATORY, CYTOPROTECTIVE | MERCK FROSST CANADA INC. (CA) | 1989-07-25 | — | — | US | disclosed |
| EP-0233763-A2 | 2-Substituted quinoline dioic acids | MERCK FROSST CANADA INC. (CA) | 1987-08-26 | — | — | EP | disclosed |