Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | PANK3 | Q9H999 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218621 | 1.00 | GRM2 (0.33) | GRM2GPR119CTSSCTSLCTSB | |
| SCHEMBL5848039 | 0.77 | CACNA1H (0.40) | GRM2GPR119PANK3 | |
| SCHEMBL534301 | 0.75 | PAX8 (0.38) | GRM2HTR2CSLC6A4 | |
| SCHEMBL25362255 | 0.72 | GRM2 (0.32) | GRM2GPR119 | |
| SCHEMBL18301296 | 0.72 | CACNA1H (0.38) | GPR119CTSSCTSLCTSBPANK3 | |
| SCHEMBL1009189 | 0.71 | NSD2 (0.45) | GRM2CTSSCTSLCTSB | |
| SCHEMBL29529170 | 0.70 | CTSS (0.46) | CTSSCTSLCTSBCTSK | |
| SCHEMBL30182704 | 0.69 | GRM2 (0.38) | GRM2SSTR4HTR2CSLC6A4 | |
| SCHEMBL27218622 | 0.69 | GRM2 (0.36) | GRM2GPR119CTSSCTSLCTSB | |
| SCHEMBL12386820 | 0.69 | GPR119 (0.37) | GRM2GPR119SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288433-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167819-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2022-08-11 | — | — | WO | disclosed |