Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29995230 | 0.83 | MYC (0.50) | TDP1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29995315 | 0.82 | PARP1 (0.42) | TDP1KDM4EALDH1A1 | |
| SCHEMBL29995876 | 0.79 | L3MBTL1 (0.46) | TDP1KDM4ECNR2MAP2K1ALDH1A1 | |
| SCHEMBL29994976 | 0.78 | MYC (0.51) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30118900 | 0.74 | L3MBTL1 (0.34) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30397636 | 0.73 | L3MBTL1 (0.62) | OPRK1HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL38658667 | 0.73 | L3MBTL1 (0.62) | OPRK1HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL15714564 | 0.72 | MYC (0.69) | TDP1KDM4EMAP2K1ALDH1A1TP53 | |
| SCHEMBL31317231 | 0.71 | OPRK1 (0.58) | TDP1KDM4EOPRK1CNR2HRH3 | |
| SCHEMBL7238484 | 0.71 | CHIA (0.66) | KDM4EOPRK1HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335043-A | PGDH inhibitors and methods of making and using | 迈欧伏特治疗公司 | 2022-11-11 | — | — | CN | disclosed |