Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29995997 | 0.78 | TDP1 (0.43) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29995876 | 0.78 | L3MBTL1 (0.46) | MYCALDH1A1KDM4EL3MBTL1ALOX15 | |
| SCHEMBL27625105 | 0.77 | MYC (0.49) | MYCSMN1; SMN2TSHRLMNAPOLB | |
| SCHEMBL30703501 | 0.76 | MYC (0.58) | MYCSMN1; SMN2TSHRLMNAPOLB | |
| SCHEMBL6264126 | 0.73 | ALDH1A1 (0.47) | MYCSMN1; SMN2TSHRLMNAPOLB | |
| SCHEMBL15434915 | 0.72 | MYC (0.66) | MYCSMN1; SMN2TSHRLMNAPOLB | |
| SCHEMBL9276285 | 0.71 | MGLL (0.37) | — | |
| SCHEMBL28406341 | 0.71 | GAA (0.36) | SMN1; SMN2LMNAPOLBKMT2AMEN1 | |
| SCHEMBL23708768 | 0.70 | NPC1 (0.60) | MYCSMN1; SMN2TSHRLMNAPOLB | |
| SCHEMBL8876281 | 0.69 | KMT2A (0.62) | MYCSMN1; SMN2TSHRLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377668-A | Inhalant formulations of PGDH inhibitors and methods of use thereof | 迈欧伏特治疗公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-115768757-A | CD206 modulators and uses and methods of making thereof | 美利坚合众国,由健康及人类服务部部长代表 | 2023-03-07 | — | — | CN | disclosed |
| CN-115335043-A | PGDH inhibitors and methods of making and using | 迈欧伏特治疗公司 | 2022-11-11 | — | — | CN | disclosed |