Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 3/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28863251 | 1.00 | CDK8 (0.53) | CDK8PTK2METCYP1A2GAA | |
| SCHEMBL28863254 | 0.85 | CDK8 (0.51) | CDK8PTK2METCYP1A2GAA | |
| SCHEMBL29657055 | 0.82 | PTK2 (0.62) | PTK2CYP1A2GAAKMT2ARAB9A | |
| SCHEMBL114189 | 0.82 | PTK2 (0.62) | PTK2CYP1A2GAAKMT2ARAB9A | |
| SCHEMBL14742495 | 0.79 | GCK (0.56) | P2RX3 | |
| SCHEMBL8794754 | 0.79 | PTK2 (0.59) | PTK2METCYP1A2GAANPC1 | |
| SCHEMBL28286246 | 0.78 | PTK2 (0.54) | CDK8PTK2METCYP1A2GAA | |
| SCHEMBL6216636 | 0.78 | PTK2 (0.57) | CDK8PTK2METCYP1A2GAA | |
| SCHEMBL13591327 | 0.77 | CDK8 (0.57) | CDK8METCYP1A2P2RX3KMT2A | |
| SCHEMBL3547563 | 0.77 | PKM (0.62) | CYP1A2KMT2AMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197130-B | Aryl urea derivative and preparation method and application thereof | 安徽医科大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-115197130-A | Aryl urea derivative and preparation method and application thereof | 安徽医科大学 | 2022-10-18 | — | — | CN | disclosed |