Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039719 | 1.00 | MAPK1 (0.49) | MAPK1KDM4EL3MBTL1NOTUMTTK | |
| SCHEMBL6882614 | 0.89 | MAPK1 (0.51) | MAPK1KDM4EL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL691501 | 0.86 | HCAR3 (0.51) | KDM4EL3MBTL1ALDH1A1MAPTHCAR3 | |
| SCHEMBL692389 | 0.84 | HCAR3 (0.38) | TTKALDH1A1HCAR3CA1CA2 | |
| SCHEMBL693629 | 0.83 | MAPK1 (0.46) | MAPK1KDM4EL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL24774145 | 0.80 | MAPK1 (0.43) | MAPK1KDM4EL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL20037705 | 0.80 | TTK (0.39) | KDM4ETTKALDH1A1RAB9ANPC1 | |
| SCHEMBL16989275 | 0.80 | KDM4E (0.47) | MAPK1KDM4EL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL3296861 | 0.79 | ALDH1A1 (0.53) | KDM4ETTKALDH1A1RAB9ANPC1 | |
| SCHEMBL1872796 | 0.79 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1ALDH1A1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288433-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167819-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2022-08-11 | — | — | WO | disclosed |