Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26828525 | 0.91 | TTK (0.41) | TTKPAX8GPR119HDAC6CCR1 | |
| SCHEMBL2031522 | 0.86 | SYK (0.38) | RAB9AMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1181429 | 0.83 | GBA1 (0.42) | TTKPAX8RAB9AMAPTALDH1A1 | |
| SCHEMBL11968939 | 0.83 | GABRG2 (0.38) | TTKPAX8ALDH1A1KDM4EGPR119 | |
| SCHEMBL56808 | 0.83 | TTK (0.37) | TTKPAX8RAB9AALDH1A1KDM4E | |
| SCHEMBL29827507 | 0.83 | GBA1 (0.42) | TTKPAX8RAB9AMAPTALDH1A1 | |
| SCHEMBL989173 | 0.83 | TTK (0.37) | TTKPAX8ALDH1A1GPR119BRD4 | |
| SCHEMBL26828516 | 0.82 | TTK (0.45) | TTKPAX8HSD17B10GPR119BRD4 | |
| SCHEMBL13115798 | 0.82 | RAB9A (0.43) | RAB9AMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL691501 | 0.82 | HCAR3 (0.51) | PAX8MAPTALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |