Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | CCR1 | P32246 | 4/20 | 0.58 |
| ▸ | CCR8 | P51685 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CCR5 | P51681 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229804 | 0.89 | CCR1 (0.54) | KDM4EMAPTCCR1CCR8SMN1; SMN2 | |
| SCHEMBL12853981 | 0.87 | LMNA (0.68) | KDM4EMAPTCCR1CCR8SMN1; SMN2 | |
| SCHEMBL30184687 | 0.87 | CCR1 (0.75) | KDM4EMAPTCCR1CCR8SMN1; SMN2 | |
| SCHEMBL1282008 | 0.87 | CCR1 (0.75) | KDM4EMAPTCCR1CCR8SMN1; SMN2 | |
| SCHEMBL13078965 | 0.86 | GSK3B (0.47) | KDM4EMAPTCCR1CCR8SMN1; SMN2 | |
| SCHEMBL13978864 | 0.84 | CCR1 (0.58) | KDM4EMAPTCCR1CCR8SMN1; SMN2 | |
| SCHEMBL9976751 | 0.83 | CCR1 (0.47) | KDM4EMAPTCCR1CCR8SMN1; SMN2 | |
| Phenanthrene SCHEMBL16685315 | 0.83 | CCR1 (0.76) | KDM4EMAPTCCR1CCR8SMN1; SMN2 | |
| SCHEMBL17931889 | 0.83 | KDM4E (0.52) | KDM4EMAPTCCR1CCR8SMN1; SMN2 | |
| SCHEMBL19767983 | 0.83 | KDM4E (0.52) | KDM4EMAPTCCR1CCR8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112250708-B | Anthracene-containing dimer skeleton ligand, preparation method thereof and application thereof in metal catalytic reaction | 中国科学院理化技术研究所 | 2023-10-13 | — | — | CN | disclosed |
| CN-112250708-A | Anthracene dimer-containing framework ligand, preparation method thereof and application thereof in metal catalytic reaction | 中国科学院理化技术研究所 | 2021-01-22 | — | — | CN | disclosed |
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | SALTIGO GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | SALTIGO GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | SALTIGO GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
| CN-101300209-A | Nickel-or iron-catalyzed carbon-carbon coupling of arylenes, alkenes and alkynes | SALTIGO GMBH (DE) | 2008-11-05 | — | — | CN | disclosed |
| EP-1924539-A1 | NICKEL OR IRON CATALYSED CARBON-CARBON COUPLING REACTION OF ARYLENES, ALKENES AND ALKINES | Saltigo GmbH (DE) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007031511-A1 | NICKEL OR IRON CATALYSED CARBON-CARBON COUPLING REACTION OF ARYLENES, ALKENES AND ALKINES | SALTIGO GMBH (DE) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007031511-A1 | NICKEL OR IRON CATALYSED CARBON-CARBON COUPLING REACTION OF ARYLENES, ALKENES AND ALKINES | SALTIGO GMBH (DE) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | MON2, ZRANB2, GRIA2 | KDM4E 3227/4885MAPT 3794/4885CCR1 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.