Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990994 | 0.85 | METAP1 (0.44) | EPHX1METAP1CYP1A2SIGMAR1ALDH1A1 | |
| SCHEMBL7361671 | 0.82 | METAP1 (0.37) | EPHX1METAP1CYP1A2SIGMAR1ALDH1A1 | |
| SCHEMBL2992784 | 0.81 | EPHX1 (0.48) | EPHX1METAP1CYP1A2CYP2D6SIGMAR1 | |
| SCHEMBL1443658 | 0.78 | SHBG (0.46) | EPHX1METAP1CYP1A2SIGMAR1ALDH1A1 | |
| SCHEMBL6877804 | 0.78 | METAP1 (0.39) | EPHX1METAP1CYP1A2SIGMAR1ALDH1A1 | |
| SCHEMBL9450351 | 0.75 | METAP1 (0.36) | METAP1CYP1A2SIGMAR1 | |
| SCHEMBL15588920 | 0.74 | METAP1 (0.38) | EPHX1METAP1ALDH1A1HPGD | |
| SCHEMBL9821330 | 0.72 | EPHX1 (0.60) | EPHX1CYP1A2CYP2D6SIGMAR1ALDH1A1 | |
| SCHEMBL9655442 | 0.72 | METAP1 (0.30) | METAP1 | |
| SCHEMBL2997439 | 0.71 | CYP1A2 (0.34) | METAP1CYP1A2SIGMAR1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-0230920-B1 | FLUID FOR TRACTION DRIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4704490-A | SYNERGISTIC MIXTURE OF ALICYCLIC HYDROCARBONS | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 1987-11-03 | — | — | US | disclosed |