Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450351 | 0.98 | METAP1 (0.36) | METAP1CYP1A2SIGMAR1 | |
| SCHEMBL7434472 | 0.88 | CYP1A2 (0.42) | METAP1CYP1A2SIGMAR1HPGDALDH1A1 | |
| SCHEMBL5087587 | 0.88 | CYP1A2 (0.42) | METAP1CYP1A2SIGMAR1HPGDALDH1A1 | |
| SCHEMBL8082088 | 0.88 | CYP1A2 (0.42) | METAP1CYP1A2SIGMAR1HPGDALDH1A1 | |
| SCHEMBL2990994 | 0.87 | METAP1 (0.44) | METAP1CYP1A2SIGMAR1HPGDALDH1A1 | |
| SCHEMBL6823998 | 0.84 | SIGMAR1 (0.39) | METAP1CYP1A2SIGMAR1EPHX1 | |
| SCHEMBL7093117 | 0.82 | SIGMAR1 (0.42) | CYP1A2SIGMAR1EPHX1 | |
| SCHEMBL9204160 | 0.80 | EPHX1 (0.36) | ALDH1A1EPHX1SHBGTP53 | |
| SCHEMBL9213980 | 0.79 | EPHX1 (0.42) | CYP1A2SIGMAR1ALDH1A1EPHX1SHBG | |
| SCHEMBL1443658 | 0.79 | SHBG (0.46) | METAP1CYP1A2SIGMAR1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242891-A1 | Production of keto acids | CAMPBELL JONATHAN (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1442009-A1 | PRODUCTION OF KETO ACIDS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037846-A1 | PRODUCTION OF KETO ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242891-A1 | Production of keto acids | PKLR, KHK, ME1 | METAP1 921/4885CYP1A2 679/4885SIGMAR1 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.