Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014639 | 0.86 | ALDH1A1 (0.70) | ALDH1A1LMNAHTTNPSR1TP53 | |
| SCHEMBL23014076 | 0.82 | ALDH1A1 (0.71) | ALDH1A1LMNAHTTNPSR1TP53 | |
| SCHEMBL23014215 | 0.81 | ALDH1A1 (0.70) | ALDH1A1LMNAHTTNPSR1TP53 | |
| SCHEMBL14048146 | 0.81 | KMT2A (0.56) | ALDH1A1LMNAHTTTP53MAPK1 | |
| SCHEMBL8752486 | 0.81 | ALDH1A1 (0.69) | ALDH1A1LMNAHTTNPSR1TP53 | |
| SCHEMBL23014059 | 0.81 | ALDH1A1 (0.65) | ALDH1A1LMNAHTTNPSR1TP53 | |
| SCHEMBL23014053 | 0.80 | POLB (0.65) | ALDH1A1LMNAHTTNPSR1TP53 | |
| SCHEMBL23014517 | 0.79 | ALDH1A1 (0.67) | ALDH1A1LMNAHTTNPSR1TP53 | |
| SCHEMBL23014211 | 0.79 | ALDH1A1 (0.67) | ALDH1A1LMNAHTTNPSR1TP53 | |
| SCHEMBL23014068 | 0.79 | ALDH1A1 (0.67) | ALDH1A1LMNAHTTNPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220305121-A1 | N-ARYL SULFONAMIDE DERIVATIVES AS VACCINE ADJUVANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305121-A1 | N-ARYL SULFONAMIDE DERIVATIVES AS VACCINE ADJUVANT | TLR1, TLR3, TLR2 | ALDH1A1 4133/4885LMNA 4318/4885HTT 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.