Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048137 | 0.86 | KMT2A (0.57) | KMT2AMEN1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL14048147 | 0.84 | KMT2A (0.55) | KMT2AMEN1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL29562518 | 0.83 | MAPT (0.63) | KMT2AMEN1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL29562355 | 0.83 | MAPT (0.63) | KMT2AMEN1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL29997641 | 0.81 | ALDH1A1 (0.70) | KMT2AMEN1MAPK1LMNACA1 | |
| SCHEMBL13577033 | 0.79 | KMT2A (0.64) | KMT2AMEN1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL11571224 | 0.78 | TSHR (0.60) | KMT2AMEN1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL6187346 | 0.77 | HTR6 (0.74) | — | |
| SCHEMBL22095984 | 0.77 | LMNA (0.58) | KMT2AMEN1MAPK1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6188378 | 0.77 | HTR6 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129288-A2 | DISULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |