Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17425354 | 0.83 | CES2 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL7243144 | 0.83 | MEN1 (0.50) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL16421152 | 0.82 | CES2 (0.34) | THRBMAPTTSHRALDH1A1CES2 | |
| SCHEMBL23983002 | 0.79 | NAAA (0.46) | THRBHTTTSHRALDH1A1CES2 | |
| SCHEMBL28145928 | 0.78 | CES2 (0.52) | TSHRALDH1A1CES2PLA2G4BCES1 | |
| Hexaethylene Glycol SCHEMBL10954529 | 0.78 | FFAR3 (0.59) | MEN1KMT2ATHRBHTTMAPT | |
| Triethylene Glycol SCHEMBL3693562 | 0.78 | FFAR3 (0.59) | MEN1KMT2ATHRBHTTMAPT | |
| Triethylene Glycol SCHEMBL5897768 | 0.78 | FFAR3 (0.59) | MEN1KMT2ATHRBHTTMAPT | |
| Tetraethylene Glycol SCHEMBL28861486 | 0.78 | FFAR3 (0.59) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL10072103 | 0.78 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115209897-A | Rapamycin analogs and uses thereof | 安纳库利亚治疗公司 | 2022-10-18 | — | — | CN | disclosed |