SCHEMBL29998469

SCHEMBL29998469

Oc1nc(-c2ccc(F)cc2F)n(-c2ccc(Cl)cc2)n1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 7/20 0.43
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ CNR2 P34972 2/20 0.38
▸ LMNA P02545 2/20 0.37
▸ PRCP P42785 1/20 0.36
▸ P2RX7 Q99572 2/20 0.36
▸ POLB P06746 1/20 0.35
▸ MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23410328 1.00 CNR1 (0.43) CNR1MEN1KMT2AATMCNR2
SCHEMBL23410885 0.78 PTGDR2 (0.43) CNR1MEN1KMT2AATMCNR2
SCHEMBL24407523 0.76 KDM4A (0.35) CNR1CNR2
SCHEMBL29655507 0.76 KDM4A (0.35) CNR1CNR2
SCHEMBL23411458 0.75 CNR1 (0.43) CNR1MEN1KMT2AATMPRCP
SCHEMBL23421466 0.75 CNR1 (0.40) CNR1MEN1KMT2AATMLMNA
SCHEMBL29635052 0.74 MALT1 (0.44) CNR1LMNAP2RX7
SCHEMBL30609050 0.74 CNR1 (0.40) CNR1MEN1KMT2AATMCNR2
SCHEMBL23447081 0.74 MALT1 (0.44) CNR1LMNAP2RX7
SCHEMBL1074268 0.70 IDO1 (0.49) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583826-B2 [(1,5-diphenyl-1H-1,2,4-triazol-3-yl)oxy]acetic acid derivatives and salts thereof, crop protection compositions comprising them, methods for producing them and use thereof as safeners BAYER AKTIENGESELLSCHAFT (DE) 2026-03-24 — — US disclosed
CN-114728915-B [ (1, 5-Diphenyl-1H-1, 2, 4-triazol-3-yl) oxy ] acetic acid derivatives and salts thereof, crop protection compositions containing same, method for producing same, and use thereof as safeners 拜耳公司 2024-08-30 — — CN disclosed
CN-116761510-A Use of [ (1, 5-diphenyl-1H-pyrazol-3-yl) oxy ] acetic acid derivatives and salts thereof and compositions containing them for reducing the phytotoxic effect of agrochemicals, in particular herbicides, on useful plants and crops 拜耳公司 2023-09-15 — — CN disclosed
US-20220388971-A1 [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND SALTS THEREOF, CROP PROTECTION COMPOSITIONS COMPRISING THEM, METHODS FOR PRODUCING THEM AND USE THEREOF AS SAFENERS BAYER AKTIENGESELLSCHAFT (DE) 2022-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583826-B2 [(1,5-diphenyl-1H-1,2,4-triazol-3-yl)oxy]acetic acid derivatives and salts thereof, crop protection compositions comprising them, methods for producing them and use thereof as safeners CBR3, CBR1, HACL2 CNR1 155/4885MEN1 4726/4885KMT2A 3535/4885
US-20220388971-A1 [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND SALTS THEREOF, CROP PROTECTION COMPOSITIONS COMPRISING THEM, METHODS FOR PRODUCING THEM AND USE THEREOF AS SAFENERS CYP4Z1, GSTO1, AADAC CNR1 2315/4885MEN1 4721/4885KMT2A 2963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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