SCHEMBL24407523

SCHEMBL24407523

Oc1nc(-c2ccc(F)cc2F)n(-c2ccc(F)cn2)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4A O75164 1/20 0.35
▸ KDM5A P29375 1/20 0.35
▸ KDM4C Q9H3R0 1/20 0.35
▸ KDM5B Q9UGL1 1/20 0.35
▸ MAPK14 Q16539 2/20 0.35
▸ KMO O15229 2/20 0.35
▸ GRM5 P41594 6/20 0.34
▸ MGLL Q99685 1/20 0.34
▸ CNR1 P21554 1/20 0.34
▸ CNR2 P34972 1/20 0.34
▸ AKT1 P31749 1/20 0.33
▸ GABRG2 P18507 1/20 0.33
▸ GABRB3 P28472 1/20 0.33
▸ GABRA5 P31644 1/20 0.33
▸ GABRA3 P34903 1/20 0.33
▸ AGER Q15109 2/20 0.32
▸ HDAC3 O15379 1/20 0.32
▸ HDAC4 P56524 1/20 0.32
▸ HDAC1 Q13547 1/20 0.32
▸ HDAC7 Q8WUI4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29655507 1.00 KDM4A (0.35) KDM4AKDM5AKDM4CKDM5BMAPK14
SCHEMBL31392413 0.78 LPAR2 (0.37) KDM4AKDM5AKDM4CKDM5BMAPK14
SCHEMBL24407576 0.78 LPAR2 (0.37) KDM4AKDM5AKDM4CKDM5BMAPK14
SCHEMBL23410328 0.76 CNR1 (0.43) CNR1CNR2
SCHEMBL29998469 0.76 CNR1 (0.43) CNR1CNR2
SCHEMBL24407471 0.75 CNR1 (0.38) MAPK14GRM5CNR1CNR2
SCHEMBL29655506 0.75 CNR1 (0.38) MAPK14GRM5CNR1CNR2
SCHEMBL30558695 0.74 MAPK14 (0.36) MAPK14GRM5CNR1CNR2
SCHEMBL24409743 0.74 P2RX7 (0.37) GRM5CNR2
SCHEMBL30519965 0.74 P2RX7 (0.37) GRM5CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617760-B2 [(5-phenyl-1-heteroaryl-1H-triazol-3-yl)oxy] acetic acid derivatives as safeners for the protection of useful plants and crop plants BAYER AKTIENGESELLSCHAFT (DE) 2026-05-05 — — US disclosed
EP-4240728-B1 DERIVATIVES OF [(5-PHENYL-1-HETEROARYL-1H-TRIAZOL-3-YL)OXY]ACETIC ACID AS SAFENERS FOR THE PROTECTION OF CULTIVATED PLANTS BAYER AG (DE) 2025-01-08 — — EP disclosed
US-20230382874-A1 [(5-PHENYL-1-HETEROARYL-1H-TRIAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2023-11-30 — — US disclosed
US-20230382874-A1 [(5-PHENYL-1-HETEROARYL-1H-TRIAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2023-11-30 — — US disclosed
US-20230382874-A1 [(5-PHENYL-1-HETEROARYL-1H-TRIAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2023-11-30 — — US disclosed
EP-4240728-A1 [(5-PHENYL-1-HETEROARYL-1H-TRIAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS Bayer Aktiengesellschaft (DE) 2023-09-13 — — EP disclosed
CN-116568136-A [ (5-phenyl-1-heteroaryl-1H-triazol-3-yl) oxy ] acetic acid derivatives as safeners for protecting useful plants and crop plants 拜耳公司 2023-08-08 — — CN disclosed
WO-2022096442-A1 [(5-PHENYL-1-HETEROARYL-1H-TRIAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 — — WO disclosed
WO-2022096442-A1 [(5-PHENYL-1-HETEROARYL-1H-TRIAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382874-A1 [(5-PHENYL-1-HETEROARYL-1H-TRIAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS CYP4Z1, PDK3, HACL2 KDM4A 3522/4885KDM5A 1703/4885KDM4C 2987/4885
US-12617760-B2 [(5-phenyl-1-heteroaryl-1H-triazol-3-yl)oxy] acetic acid derivatives as safeners for the protection of useful plants and crop plants CBR3, CBR1, HACL2 KDM4A 4015/4885KDM5A 3268/4885KDM4C 1914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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